Title : Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells.

Pub. Date : 2008 Oct 21

PMID : 18845679






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We show that in human cells, PCNA is monoubiquitinated in response to methyl methanesulfonate and mitomycin C, as well as UV light, albeit with different kinetics, but not in response to bleomycin or camptothecin. Methyl Methanesulfonate proliferating cell nuclear antigen Homo sapiens
2 Failure to ubiquitinate PCNA results in substantial sensitivity to UV and methyl methanesulfonate, but not to camptothecin or bleomycin. Methyl Methanesulfonate proliferating cell nuclear antigen Homo sapiens