Title : [Regulatory function of tacrolimus and CsA on CD4/CD8 T lymphocyte subgroups and costimulators on them in allo-liver recipients].

Pub. Date : 2008 Oct

PMID : 18845086






2 Functional Relationships(s)
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1 FK506 can not only inhibit the expression of positive co-stimulatory molecules CD28 and ICOS but also promote the expression of negative co-stimulatory molecule CD152, while CsA can exert its immunosuppressive effect mainly through promoting the expression of CD152. Tacrolimus cytotoxic T-lymphocyte associated protein 4 Homo sapiens
2 FK506 can not only inhibit the expression of positive co-stimulatory molecules CD28 and ICOS but also promote the expression of negative co-stimulatory molecule CD152, while CsA can exert its immunosuppressive effect mainly through promoting the expression of CD152. Tacrolimus cytotoxic T-lymphocyte associated protein 4 Homo sapiens