Title : Association between the 2756A> G variant in the gene encoding methionine synthase and myocardial infarction in Tunisian patients.

Pub. Date : 2008

PMID : 18844488






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Methionine synthase (MS), a vitamin B(12)-dependent enzyme, catalyses the remethylation of homocysteine to methionine using a methyl group donated by 5-methyltetra-hydrofolate, which is the major circulating form of folate in the body. Folic Acid 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens
2 Methionine synthase (MS), a vitamin B(12)-dependent enzyme, catalyses the remethylation of homocysteine to methionine using a methyl group donated by 5-methyltetra-hydrofolate, which is the major circulating form of folate in the body. Folic Acid 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens
3 Functional genetic variants of the MS may alter tHcy as well as folate levels which are independent risk factors for CAD. Folic Acid 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens
4 The influence of a common genetic polymorphism 2756A>G of the MS gene (MTR) on plasma tHcy, folate and vitamin B(12) levels and its relation to the risk of myocardial infarction (MI) in a Tunisian case-control study was investigated. Folic Acid 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens