Pub. Date : 2008 Dec 12
PMID : 18840612
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling. | Lysine | tumor protein p53 | Homo sapiens |
| 2 | Recently, lysine methylation has been shown also to play a role in regulating non-histone proteins, including the tumor suppressor protein p53 (Huang, J., and Berger, S. L. (2008) Curr. | Lysine | tumor protein p53 | Homo sapiens |
| 3 | Here, we identify a novel p53 species that is dimethylated at lysine 382 (p53K382me2) and show that the tandem Tudor domain of the DNA damage response mediator 53BP1 acts as an "effector" for this mark. | Lysine | tumor protein p53 | Homo sapiens |