Title : Glibenclamide exerts an antitumor activity through reactive oxygen species-c-jun NH2-terminal kinase pathway in human gastric cancer cell line MGC-803.

Pub. Date : 2008 Dec 15

PMID : 18840412






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Glibenclamide exerts an antitumor activity through reactive oxygen species-c-jun NH2-terminal kinase pathway in human gastric cancer cell line MGC-803. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
2 Taken together, our study reveals that glibenclamide exerts an antitumor activity in MGC-803 cells by activating ROS-dependent, JNK-driven cell apoptosis. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens