Title : G protein-coupled receptors go extracellular: RhoA integrates the integrins.

Pub. Date : 2008 Aug

PMID : 18829842






1 Functional Relationships(s)
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1 Intriguingly, GPCR ligands such as thrombin, sphingosine-1-phosphate, and lysophosphatidic acid, which signal through G(12/13) and activate RhoA, have recently been shown to induce the expression of the extracellular matrix protein Cyr61 (i.e., CCN1). lysophosphatidic acid ras homolog family member A Homo sapiens