Pub. Date : 2008 Oct 1
PMID : 18829552
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance. | Nucleosides | RAD50 double strand break repair protein | Homo sapiens |
| 2 | Using gamma-H2AX as a marker for changes in chromatin structure, we show that Mre11, Rad50, Nbs1, and phosphorylated ATM respond to nucleoside analogue-induced stalled replication forks by forming nuclear foci that colocalize with gamma-H2AX within 2 hours. | Nucleosides | RAD50 double strand break repair protein | Homo sapiens |