Title : Protective mechanisms of Aralia continentalis extract against tert-butyl hydroperoxide-induced hepatotoxicity: in vivo and in vitro studies.

Pub. Date : 2008 Nov

PMID : 18824057






1 Functional Relationships(s)
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1 Taken together, these results suggest that the protective effects of AC against t-BHP-induced hepatotoxicity may, at least in part, be due to its ability to scavenge ROS and to regulate the antioxidant enzyme HO-1 via the ERK1/2 and p38/Nrf2 signaling pathways. tert-Butylhydroperoxide nuclear factor, erythroid derived 2, like 2 Mus musculus