Title : Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis.

Pub. Date : 2009 Sep

PMID : 18815879






1 Functional Relationships(s)
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1 Pathway analysis using these genes revealed that DNA repair pathways, including BRCA1 pathway, PTEN, a gene whose loss of function is associated with resistance to chemotherapy, and TOP2A, the molecular target of anthracyclines, are significantly downregulated in MBCs compared to basal-like IDCs. Anthracyclines DNA topoisomerase II alpha Homo sapiens