Title : Cardiovascular and gastrointestinal toxicity of selective cyclo-oxygenase-2 inhibitors in man.

Pub. Date : 2008 Aug

PMID : 18812633






2 Functional Relationships(s)
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1 Selective NSAIDs were specifically designed to preferentially inhibit the cyclooxygenase-2 (COX-2), an inducible enzyme mediating the production of inflammatory eicosanoids in the joints but sparing the endogenous protective eicosanoids in the stomach. Eicosanoids mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Selective NSAIDs were specifically designed to preferentially inhibit the cyclooxygenase-2 (COX-2), an inducible enzyme mediating the production of inflammatory eicosanoids in the joints but sparing the endogenous protective eicosanoids in the stomach. Eicosanoids mitochondrially encoded cytochrome c oxidase II Homo sapiens