Title : Fragmentation of doubly-protonated peptide ion populations labeled by H/D exchange with CD(3)OD.

Pub. Date : 2006

PMID : 18802500






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Doubly-protonated bradykinin (RPPGFSPFR) and an angiotensin III analogue (RVYIFPF) were subjected to hydrogen/deuterium (H/D) exchange with CD(3)OD in a Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. Deuterium kininogen 1 Homo sapiens
2 A bimodal distribution of deuterium incorporation was present for bradykinin after H/D exchange for 90 s at a CD(3)OD pressure of 4 x 10(-7) Torr, indicating the existence of at least two distinct populations. Deuterium kininogen 1 Homo sapiens
3 Bradykinin ion populations corresponding to 0-2 and 5-11 deuteriums (i.e., D(0), D(1), D(2), D(5), D(6), D(7), D(8), D(9), D(10), and D(11)) were each monoisotopically selected and fragmented via sustained off-resonance irradiation (SORI) collision-induced dissociation (CID). Deuterium kininogen 1 Homo sapiens