Title : Actin filament assembly by myristoylated alanine-rich C kinase substrate-phosphatidylinositol-4,5-diphosphate signaling is critical for dendrite branching.

Pub. Date : 2008 Nov

PMID : 18799624






3 Functional Relationships(s)
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1 Actin filament assembly by myristoylated alanine-rich C kinase substrate-phosphatidylinositol-4,5-diphosphate signaling is critical for dendrite branching. Phosphatidylinositol 4,5-Diphosphate myristoylated alanine rich protein kinase C substrate Homo sapiens
2 Here, we show that increasing the level of myristoylated, alanine-rich C kinase substrate (MARCKS), a prominent substrate of protein kinase C and a phosphatidylinositol-4,5-diphosphate [PI(4,5)P2] sequestration protein highly expressed in the brain, enhanced branching and growth of dendrites both in vitro and in vivo. Phosphatidylinositol 4,5-Diphosphate myristoylated alanine rich protein kinase C substrate Homo sapiens
3 Here, we show that increasing the level of myristoylated, alanine-rich C kinase substrate (MARCKS), a prominent substrate of protein kinase C and a phosphatidylinositol-4,5-diphosphate [PI(4,5)P2] sequestration protein highly expressed in the brain, enhanced branching and growth of dendrites both in vitro and in vivo. Phosphatidylinositol 4,5-Diphosphate myristoylated alanine rich protein kinase C substrate Homo sapiens