Title : Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers.

Pub. Date : 2008 Dec 4

PMID : 18794809






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 POX is markedly elevated during p53-induced apoptosis and generates proline-dependent reactive oxygen species (ROS), specifically superoxide radicals, to induce apoptosis through both mitochondrial and death receptor pathways. Reactive Oxygen Species proline dehydrogenase 1 Homo sapiens
2 POX is markedly elevated during p53-induced apoptosis and generates proline-dependent reactive oxygen species (ROS), specifically superoxide radicals, to induce apoptosis through both mitochondrial and death receptor pathways. Reactive Oxygen Species proline dehydrogenase 1 Homo sapiens