Title : A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells.

Pub. Date : 2008 Sep 15

PMID : 18794110






1 Functional Relationships(s)
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1 Using a computational virtual screening strategy, we have identified a unique small molecule inhibitor that serves as a suicide substrate for MIF, resulting in the covalent modification of the catalytically active NH(2)-terminal proline. Proline macrophage migration inhibitory factor Homo sapiens