Title : Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway.

Pub. Date : 2008 Sep

PMID : 18790767






1 Functional Relationships(s)
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1 Mechanistically, bortezomib induced a G2-M-phase cell cycle arrest and p53-independent apoptosis associated with caspase cleavage and Noxa induction. Bortezomib tumor protein p53 Homo sapiens