Pub. Date : 2008 Oct
PMID : 18789871
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oral glucose uptake alters the function of immune cells and an elevation of systemic CXCL8 was described. | Glucose | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 2 | Monocytes secrete high amounts of CXCL8 and therefore it was analyzed whether glucose or insulin upregulate monocytic CXCL8 release. | Glucose | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 3 | CXCL8 was also higher when determined in the cell lysate of leukocytes 2h after glucose uptake whereas plasma CXCL8 levels were significantly reduced. | Glucose | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 4 | In summary, these data indicate that oral glucose uptake in insulin-sensitive adults is associated with elevated monocytic and reduced systemic CXCL8. | Glucose | C-X-C motif chemokine ligand 8 | Homo sapiens |