Title : Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells.

Pub. Date : 2008 Nov 14

PMID : 18782770






1 Functional Relationships(s)
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1 Direct measurement of ligand shedding confirmed that LPA treatment stimulated shedding of multiple EGFR ligands, but paradoxically, IGF-1 had little effect on the shedding rate of any ligand, including amphiregulin. lysophosphatidic acid epidermal growth factor receptor Homo sapiens