Title : Influence of enzyme-inducing antiepileptic drugs on trough level of imatinib in glioblastoma patients.

Pub. Date : 2008 Sep

PMID : 18781906






1 Functional Relationships(s)
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1 Since CYP3A4 is the major isozyme involved in the metabolism of imatinib, we investigated the influence of EIAEDs on imatinib pharmacokinetics (pk). Imatinib Mesylate cytochrome P450 family 3 subfamily A member 4 Homo sapiens