Title : 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose.

Pub. Date : 2009 Mar 25

PMID : 18778749






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A NADPH/NADP(+) ratio of ten or higher was required for efficient microsomal 11beta-HSD1 reductase activity. NADP RNA, U1 small nuclear 1 Homo sapiens
2 A NADPH/NADP(+) ratio of ten or higher was required for efficient microsomal 11beta-HSD1 reductase activity. NADP RNA, U1 small nuclear 1 Homo sapiens
3 11beta-HSD1 dehydrogenase activity was observed in H4IIE cells only at subphysiological glucose levels, indicating a highly efficient supply of substrate for H6PDH and NADPH generation in the ER-lumen. NADP RNA, U1 small nuclear 1 Homo sapiens