Title : N- and O-glycans are not directly involved in the oligomerization and apical sorting of GPI proteins.

Pub. Date : 2008 Dec

PMID : 18778408






1 Functional Relationships(s)
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1 Interestingly, when cells are depleted of cholesterol and treated with tunicamycin, treatments that by themselves do not affect PLAP sorting, PLAP is not able to oligomerize and is missorted to the basolateral surface, thus supporting an indirect role of N-glycosylation, possibly mediated by a raft-associated glycosylated interactor. Tunicamycin alkaline phosphatase, placental Homo sapiens