Title : Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function.

Pub. Date : 2008 Nov

PMID : 18765732






1 Functional Relationships(s)
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1 We now show that A. phagocytophilum infection also enhances the binding of CDP to the promoters of human neutrophil peptide 1 and C/EBPepsilon--molecules important for neutrophil defense and maturation--suggesting that this is a general strategy used by this pathogen to alter polymorphonuclear leukocyte function. Cytidine Diphosphate CCAAT enhancer binding protein epsilon Homo sapiens