Title : Rac1 signaling regulates CTGF/CCN2 gene expression via TGFbeta/Smad signaling in chondrocytes.

Pub. Date : 2009 Mar

PMID : 18760941






1 Functional Relationships(s)
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1 We also show that the Smad site in the CTGF/CCN2 promoter is responsive to both Rac1 inhibition and cytochalasin D treatment, suggesting a role of TGFbeta/Smad signaling in mediating the effects of actin dynamics and Rac1. Cytochalasin D transforming growth factor beta 1 Homo sapiens