Title : Ectodomain cleavage of the EGF ligands HB-EGF, neuregulin1-beta, and TGF-alpha is specifically triggered by different stimuli and involves different PKC isoenzymes.

Pub. Date : 2008 Dec

PMID : 18757500






2 Functional Relationships(s)
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1 In contrast, phorbol 12-myristate-13-acetate (TPA) -induced cleavage of HB-EGF, NRG, and TGF-alpha was dependent on PKC and sensitive to BB94 inhibition. Tetradecanoylphorbol Acetate transforming growth factor alpha Mus musculus
2 In contrast, phorbol 12-myristate-13-acetate (TPA) -induced cleavage of HB-EGF, NRG, and TGF-alpha was dependent on PKC and sensitive to BB94 inhibition. Tetradecanoylphorbol Acetate transforming growth factor alpha Mus musculus