Title : The role of JUN in the regulation of PRKCC-mediated STAR expression and steroidogenesis in mouse Leydig cells.

Pub. Date : 2008 Nov

PMID : 18755854






2 Functional Relationships(s)
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1 MA-10 mouse Leydig tumor cells treated with an activator of PRKCC, phorbol 12-myristate 13-acetate (PMA), demonstrated increases in the expression of the STAR and CYP11A1 proteins and progesterone synthesis, which coincided with the expression and phosphorylation of JUN (P-JUN). Tetradecanoylphorbol Acetate steroidogenic acute regulatory protein Mus musculus
2 MA-10 mouse Leydig tumor cells treated with an activator of PRKCC, phorbol 12-myristate 13-acetate (PMA), demonstrated increases in the expression of the STAR and CYP11A1 proteins and progesterone synthesis, which coincided with the expression and phosphorylation of JUN (P-JUN). Tetradecanoylphorbol Acetate steroidogenic acute regulatory protein Mus musculus