Title : Ganglioside GM1 mediates decapacitation effects of SVS2 on murine spermatozoa.

Pub. Date : 2008 Dec

PMID : 18753612






3 Functional Relationships(s)
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Protein Name
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1 When the ejaculated spermatozoa were stained with a cholera toxin subunit B (CTB) that preferably interacts with ganglioside GM1, another member of the lipid rafts, the staining pattern of the sperm was the same as the binding pattern of SVS2. G(M1) Ganglioside phosphate cytidylyltransferase 1, choline, beta isoform Mus musculus
2 When the ejaculated spermatozoa were stained with a cholera toxin subunit B (CTB) that preferably interacts with ganglioside GM1, another member of the lipid rafts, the staining pattern of the sperm was the same as the binding pattern of SVS2. G(M1) Ganglioside phosphate cytidylyltransferase 1, choline, beta isoform Mus musculus
3 Interestingly, SVS2 and CTB competitively bound to the sperm surface with each other, suggesting that the binding targets of both molecules are the same, that is, GM1. G(M1) Ganglioside phosphate cytidylyltransferase 1, choline, beta isoform Mus musculus