Title : Discovery of novel series of benzoic acid derivatives containing biphenyl ether moiety as potent and selective human beta(3)-adrenergic receptor agonists: Part IV.

Pub. Date : 2008 Sep 15

PMID : 18752946






3 Functional Relationships(s)
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1 Discovery of novel series of benzoic acid derivatives containing biphenyl ether moiety as potent and selective human beta(3)-adrenergic receptor agonists: Part IV. Benzoic Acid adrenoceptor beta 3 Homo sapiens
2 Identification and SAR study of novel series of beta(3)-AR agonists with benzoic acid are described. Benzoic Acid adrenoceptor beta 3 Homo sapiens
3 Compounds 7g and 7k, with the bulky aliphatic-substituted group at 2-position of benzoic acid moiety, were identified as potent and selective beta(3)-AR agonists. Benzoic Acid adrenoceptor beta 3 Homo sapiens