Title : Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index.

Pub. Date : 2009

PMID : 18752089






3 Functional Relationships(s)
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1 AIMS: This joint analysis aimed to clarify whether IL6 -174G>C was associated with glucose and circulating interleukin-6 concentrations as well as body mass index (BMI). Glucose interleukin 6 Homo sapiens
2 IL6 -174 C-allele carriers had significantly lower fasting glucose (-0.091 mmol/L, P=0.014). Glucose interleukin 6 Homo sapiens
3 CONCLUSIONS: Our data suggest that C-allele carriers of the IL6 -174G>C polymorphism have lower fasting glucose levels on average, which substantiates previous findings of decreased T2DM risk of these subjects. Glucose interleukin 6 Homo sapiens