Pub. Date : 2009 Jan 1
PMID : 18729824
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions. | Physostigmine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | The role of the functional architecture of the HuAChE (human acetylcholinesterase) in reactivity toward the carbamates pyridostigmine, rivastigmine and several analogues of physostigmine, that are currently used or considered for use as drugs for Alzheimer"s disease, was analysed using over 20 mutants of residues that constitute the interaction subsites in the active centre. | Physostigmine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |