Pub. Date : 2008 Oct
PMID : 18728628
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP2D6 catalyzes the conversion of risperidone to the active metabolite 9-OH-risperidone. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | The question whether CYP2D6 activity is important for the level of the "active moiety" (ie, the sum of risperidone and 9-OH-risperidone) is controversial. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 3 | Concentration-to-dose (C:D) ratios of risperidone and 9-OH-risperidone in 218 patients were associated with the number of concomitantly used substrates or inhibitors of CYP2D6. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |