Title : The JNK signaling pathway is involved in sodium-selenite-induced apoptosis mediated by reactive oxygen in HepG2 cells.

Pub. Date : 2008 May

PMID : 18728404






2 Functional Relationships(s)
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1 In this study, we showed that selenite-induced apoptosis in HepG2 cells was mediated by ROS that activated JNK to regulate apoptosis. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
2 These results revealed that JNK might be involved in selenite-induced ROS-mediated apoptosis in HepG2 cells. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens