Title : Membrane progestin receptors alpha and gamma in renal epithelium.

Pub. Date : 2008 Dec

PMID : 18722485






2 Functional Relationships(s)
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1 We first focused our investigations on mPRalpha and gamma by analyzing three parameters 1/ their distribution along the mouse nephron and their subcellular location in native kidney, 2/ the ability of progesterone to stimulate ERK pathway and/or Ca(2+) release from internal stores in native kidney structures and 3/ the cellular localization of mPRalpha and its molecular determinants in heterologous expression system. Progesterone S100 calcium binding protein A6 (calcyclin) Mus musculus
2 We first focused our investigations on mPRalpha and gamma by analyzing three parameters 1/ their distribution along the mouse nephron and their subcellular location in native kidney, 2/ the ability of progesterone to stimulate ERK pathway and/or Ca(2+) release from internal stores in native kidney structures and 3/ the cellular localization of mPRalpha and its molecular determinants in heterologous expression system. Progesterone S100 calcium binding protein A6 (calcyclin) Mus musculus