Pub. Date : 2008 Aug
PMID : 18717824
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Calcitriol blunts pro-atherosclerotic parameters through NFkappaB and p38 in vitro. | Calcitriol | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Furthermore, the LPS induced nuclear factor kappaB (NFkappaB)-p65 DNA-binding activity was also decreased by calcitriol. | Calcitriol | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | CONCLUSIONS: The decreased NFkappaB and p38 activities followed by calcitriol treatment may explain the anti-inflammatory/atherosclerotic properties of calcitriol that were observed previously and were emphasized in this study, demonstrating the inhibitory effect of calcitriol on the pro-inflammatory parameters: adhesion molecules, RAGE and IL-6. | Calcitriol | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | CONCLUSIONS: The decreased NFkappaB and p38 activities followed by calcitriol treatment may explain the anti-inflammatory/atherosclerotic properties of calcitriol that were observed previously and were emphasized in this study, demonstrating the inhibitory effect of calcitriol on the pro-inflammatory parameters: adhesion molecules, RAGE and IL-6. | Calcitriol | nuclear factor kappa B subunit 1 | Homo sapiens |