Pub. Date : 2008 Oct
PMID : 18708991
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Risperidone is metabolized to its active metabolite, 9-hydroxyrisperidone, mainly by the cytochrome P450 enzymes CYP2D6 and 3A4. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | The CYP2D6 genotype in these 46 patients was again associated with risperidone C/D (P = 0.001) but not with 9-hydroxyrisperidone C/D or active moiety C/D, as previously shown by our group in 37 of these patients. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |