Pub. Date : 2008 Oct 1
PMID : 18703021
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A number of Pgp substrates (quinidine, amprenavir, irinotecan, topotecan, atorvastatin and erythromycin) induced net digoxin secretion, as did the non-Pgp substrate artemisinin. | Atorvastatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Of the compounds that increased Pgp secretion, quinidine, topotecan, atorvastatin and amprenavir pre-exposure also elevated MDR1 mRNA levels, whereas erythromycin, irinotecan and artemisinin displayed no change in transcript levels. | Atorvastatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Of the compounds that increased Pgp secretion, quinidine, topotecan, atorvastatin and amprenavir pre-exposure also elevated MDR1 mRNA levels, whereas erythromycin, irinotecan and artemisinin displayed no change in transcript levels. | Atorvastatin | ATP binding cassette subfamily B member 1 | Homo sapiens |