Title : Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase.

Pub. Date : 2008 Oct 17

PMID : 18697738






1 Functional Relationships(s)
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1 Insulin release in response to pyruvate alone, 2-aminobicyclo[2,2,1]heptane-2-carboxylic acid (BCH) plus glutamine, or methyl succinate plus beta-hydroxybutyrate was also decreased in the PC knockdown cells. 3-Hydroxybutyric Acid insulin Homo sapiens