Title : A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages.

Pub. Date : 2008 Jul 31

PMID : 18671842






1 Functional Relationships(s)
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1 CONCLUSION: Here we show that furoxan-aspirin, B8, significantly reduces TNFalpha release from both monocytes and macrophages and suggest that inhibition of NF-kappaB activation is a likely mechanism for the effect. Aspirin nuclear factor kappa B subunit 1 Homo sapiens