Title : Flavonoids as substrates and inhibitors of myeloperoxidase: molecular actions of aglycone and metabolites.

Pub. Date : 2008 Aug

PMID : 18620432






2 Functional Relationships(s)
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1 Immunohistochemical staining showed that a quercetin metabolite was colocalized with macrophages, MPO, and dityrosine, an MPO-derived oxidation product of tyrosine, in human atherosclerotic aorta. dityrosine myeloperoxidase Homo sapiens
2 Quercetin and the plasma metabolites inhibited the formation of dityrosine catalyzed by the MPO enzyme and HL-60 cells in a dose-dependent manner. dityrosine myeloperoxidase Homo sapiens