Title : Folate and vitamin B6 intake and risk of colon cancer in relation to p53 expression.

Pub. Date : 2008 Sep

PMID : 18619459






3 Functional Relationships(s)
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1 Similarly, high vitamin B(6) intake conferred a protective effect on p53-overexpressing cancers (top versus bottom quintile: RR, 0.57; 95% CI, 0.35-0.94; P(heterogeneity) = .01) but had no effect on p53 wild-type tumors. Niacinamide tumor protein p53 Homo sapiens
2 Similarly, high vitamin B(6) intake conferred a protective effect on p53-overexpressing cancers (top versus bottom quintile: RR, 0.57; 95% CI, 0.35-0.94; P(heterogeneity) = .01) but had no effect on p53 wild-type tumors. Niacinamide tumor protein p53 Homo sapiens
3 CONCLUSIONS: We found that low folate and vitamin B(6) intake was associated with an increased risk of p53-overexpressing colon cancers but not wild-type tumors. Niacinamide tumor protein p53 Homo sapiens