Title : Growth hormone alters lipolysis and hormone-sensitive lipase activity in 3T3-F442A adipocytes.

Pub. Date : 1991 Aug

PMID : 1861630






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 In these cells, GH alone produced a dose-dependent increase in the release of glycerol after 24 to 48 hours. Glycerol growth hormone 1 Homo sapiens
2 Under each condition, the stimulation of glycerol release was accompanied by a GH-induced increase in the activity of hormone-sensitive lipase (HSL), a key lipolytic enzyme. Glycerol growth hormone 1 Homo sapiens
3 The increase in HSL activity by epinephrine, like glycerol release, was potentiated by GH. Glycerol growth hormone 1 Homo sapiens
4 However, in contrast to the chronic effect of GH, short-term (30-minute) incubation with GH inhibited epinephrine-stimulated glycerol release, a characteristic transient antilipolytic effect of GH. Glycerol growth hormone 1 Homo sapiens
5 However, in contrast to the chronic effect of GH, short-term (30-minute) incubation with GH inhibited epinephrine-stimulated glycerol release, a characteristic transient antilipolytic effect of GH. Glycerol growth hormone 1 Homo sapiens