Title : Effect of the aging process on the gender and phenobarbital dependent expression of glutathione S-transferase subunits in brown Norway rat liver.

Pub. Date : 1991 Jul 15

PMID : 1859462






3 Functional Relationships(s)
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1 Effect of the aging process on the gender and phenobarbital dependent expression of glutathione S-transferase subunits in brown Norway rat liver. Phenobarbital hematopoietic prostaglandin D synthase Rattus norvegicus
2 The effect of age, gender and phenobarbital treatment on the hepatic cytosolic glutathione S-transferase subunit composition was studied in Brown Norway rats. Phenobarbital hematopoietic prostaglandin D synthase Rattus norvegicus
3 In all the age groups studied phenobarbital administration (45 mg/kg body weight, i.p., once a day for 7 days) doubled total glutathione S-transferase protein in both genders and affected the subunit composition in a significant way, emphasizing the already existing differences between genders. Phenobarbital hematopoietic prostaglandin D synthase Rattus norvegicus