Title : Two newly synthesized 5-methyltetrahydrofolate-like compounds inhibit methionine synthase activity accompanied by cell cycle arrest in G1/S phase and apoptosis in vitro.

Pub. Date : 2008 Aug

PMID : 18594211






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cobalamin-dependent methionine synthase, with a cofactor of vitamin B12, catalyzes the reaction of 5-methyltetrahydrofolate and homocysteine to form methionine and tetrahydrofolate, which takes a core position in folate cycle, one-carbon-unit transfer, and sulfur amino acid pathways. Folic Acid 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens