Title : Inhibitory effects of salvianolic acid B on the high glucose-induced mesangial proliferation via NF-kappaB-dependent pathway.

Pub. Date : 2008 Jul

PMID : 18591779






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These results indicated that Sal B could inhibit high glucose-induced mesangial cells proliferation and extracellular matrix production in a dose-dependent manner, partially through modulating the cell-cycle progress and MMP-2 and MMP-9 activities via suppressing NF-kappaB activation, suggesting that Sal B may be a promising agent for treating diabetic nephropathy. salvianolic acid B matrix metallopeptidase 2 Homo sapiens