Title : Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer.

Pub. Date : 2008 Aug 1

PMID : 18589402






3 Functional Relationships(s)
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Protein Name
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1 Overexpression of hENT1 is associated with changes in cell cycle profile, in a variable manner depending on the particular cell type, thus suggesting a metabolic link between hENT1-mediated transport processes and the enzymatic machinery responsible for intracellular nucleoside metabolism. Nucleosides solute carrier family 29 member 1 (Augustine blood group) Homo sapiens
2 Overexpression of hENT1 is associated with changes in cell cycle profile, in a variable manner depending on the particular cell type, thus suggesting a metabolic link between hENT1-mediated transport processes and the enzymatic machinery responsible for intracellular nucleoside metabolism. Nucleosides solute carrier family 29 member 1 (Augustine blood group) Homo sapiens
3 In summary, hENT1 overexpression is associated with alterations in nucleoside enzymatic machinery and cell cycle progression in cultured cells and enhances gemcitabine action in vivo. Nucleosides solute carrier family 29 member 1 (Augustine blood group) Homo sapiens