Title : Characterization of asymmetric fluorogenic phosphonates as probes for developing organophosphorus hydrolases with broader stereoselectivity.

Pub. Date : 2008 Sep 25

PMID : 18588863






2 Functional Relationships(s)
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Protein Name
Organism
1 AChE was 90-95% inhibited by all Flu-OPs (0.36-0.9(M) and then was reactivated by either 2-PAM or TOX. Obidoxime Chloride acetylcholinesterase (Cartwright blood group) Homo sapiens
2 TOX was also shown to be a better reactivator than 2-PAM for AChE inhibited by the nerve agents VX and cyclosarin. Obidoxime Chloride acetylcholinesterase (Cartwright blood group) Homo sapiens