Title : Computational discovery of novel low micromolar human pregnane X receptor antagonists.

Pub. Date : 2008 Sep

PMID : 18579710






1 Functional Relationships(s)
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Protein Name
Organism
1 A recent novel pharmacophore for PXR antagonists was developed using three azoles and consisted of two hydrogen bond acceptor regions and two hydrophobic features. Azoles nuclear receptor subfamily 1 group I member 2 Homo sapiens