Title : Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation.

Pub. Date : 2008 Aug

PMID : 18579679






1 Functional Relationships(s)
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1 Based on our results, we propose that sdf1-expressing mesodermal cells, which overlie the endodermal layer, guide the cxcr4a-expressing endodermal cells to the dorsal side of the embryo during gastrulation, possibly through a PIP(3)-independent pathway. pip(3) chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) Danio rerio