Title : Double oxygen-sensing vector system for robust hypoxia/ischemia-regulated gene induction in cardiac muscle in vitro and in vivo.

Pub. Date : 2008 Sep

PMID : 18578010






1 Functional Relationships(s)
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1 Hypoxia-responsive cis elements were used in tandem with a single proline-modified oxygen-dependent degradation (ODD) domain of hypoxia-inducible factor-1alpha to form a double oxygen-sensing vector system (DOSVS). Proline hypoxia inducible factor 1 subunit alpha Homo sapiens