Title : Central administration of interferon-alpha enhances rat sympathetic nerve activity to the spleen.

Pub. Date : 1991 Apr 15

PMID : 1857556






1 Functional Relationships(s)
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1 Intracerebroventricular injection of recombinant human interferon-alpha (IFN-alpha) in a dose of 1 x 10(4) U, but not 3 x 10(3) U, produced a long-lasting (at least for 60 min) increase (2.5-5 times the preinjection level) in the electrical activity of splenic sympathetic nerve filaments in urethane-alpha chloralose-anesthetized rats. Urethane interferon alpha 1 Homo sapiens