Pub. Date : 2008 Aug 1
PMID : 18572410
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PON1 hydrolyzes organophosphates, arylesters and lactones, whereas the lactones activity is assumed as the physio/pathological one. | Lactones | paraoxonase 1 | Homo sapiens |
| 2 | Based on such calculations the ligands-PON1 interactions were characterized, and relating lactones rate of hydrolysis revealed an inverse correlation with the docking energy of the ligands-PON1 complex, and a direct correlation with the lactone side chain length. | Lactones | paraoxonase 1 | Homo sapiens |
| 3 | Based on such calculations the ligands-PON1 interactions were characterized, and relating lactones rate of hydrolysis revealed an inverse correlation with the docking energy of the ligands-PON1 complex, and a direct correlation with the lactone side chain length. | Lactones | paraoxonase 1 | Homo sapiens |
| 4 | In conclusion, this study characterized the PON1 possible active site and proposes a tool which may make it possible to envisage the structure of potential endogenous and exogenous lactones such as the PON1 ligand. | Lactones | paraoxonase 1 | Homo sapiens |
| 5 | In conclusion, this study characterized the PON1 possible active site and proposes a tool which may make it possible to envisage the structure of potential endogenous and exogenous lactones such as the PON1 ligand. | Lactones | paraoxonase 1 | Homo sapiens |