Title : Binding of paroxetine to the serotonin transporter in membranes from different cells, subcellular fractions and species.

Pub. Date : 2009 Feb

PMID : 18563559






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Binding of paroxetine to the serotonin transporter in membranes from different cells, subcellular fractions and species. Paroxetine solute carrier family 6 member 4 Homo sapiens
2 The main finding was that the K (D) of paroxetine binding to the SERT was the same for platelet and nerve ending (synaptosomal) membranes. Paroxetine solute carrier family 6 member 4 Homo sapiens
3 Binding at two different temperatures for several of the fractions suggests that paroxetine-SERT interaction is entropy-driven. Paroxetine solute carrier family 6 member 4 Homo sapiens